Searchable abstracts of presentations at key conferences in endocrinology

ea0022p306 | Diabetes | ECE2010

Exercise-related levels of acetylcarnitine in skeletal muscle of individuals with type 1 diabetes in Eu- and hyperglycaemia assessed by 1H-MR spectroscopy

Jenni Stefan , Boss Andreas , Kreis Roland , Ith Michael , Christ Emanuel , Boesch Chris , Stettler Christoph

Background: Acetylcarnitine (AC) is involved in intramyocellular fuel metabolism during exercise. So far, little is known on exercise-associated myocellular AC levels in patients with type 1 diabetes. In particular, it is unknown whether AC levels differ according to glucose values in diabetic patients. 1H magnetic resonance spectroscopy (MRS) of the skeletal muscle allows for the non-invasive assessment of acetylcarnitine (AC) accumulation. The present study assess...